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br Methods br Results br Discussion Skin
2020-05-08
Methods Results Discussion Skin biopsy and microneurography have both been described as useful tools in the diagnosis of PAN, directly identifying peripheral sympathetic fibers without the mediation of specific AM 281 mg organs (Donadio et al., 2005, Donadio et al., 2012a, Donadio and Ligu
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br Materials and methods br
2020-05-08
Materials and methods Results Artemis has been reported to possess 5′–3′ exonuclease activity in vitro on ssDNA, as well as DNA-PK-dependent endonuclease activity on single-strand overhang and hairpin DNA structures [11]. However, enzymes within the metallo-β-lactamase family typically contain
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br MCADD review br Funding None br Introduction
2020-05-08
MCADD review Funding None. Introduction Bacteroides species are obligate anaerobes, Gram-negative, and non-spore-forming bacteria and 21 species of this genus are found particularly in the oral cavity and gastrointestinal tract in vertebrates [1,2]. B. fragilis is the most common 5-ht rece
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The data regarding the association between
2020-05-08
The data regarding the association between COMT Val158/108Met and cognitive function are divergent [10,11,12,22,24,25,26,27,28]. Better performance on the ROCF immediate and delayed recall test among veterans with PTSD who were Met carriers, compared to Val/Val homozygotes, agrees with findings show
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Ten non FH ADH probands
2020-05-08
Ten non-FH ADH probands fulfilled the diagnostic criteria of hyperabsorbers. Table 2 shows the main lipid characteristics of these subjects and of 10 non-hyperabsorber probands used for comparison. There were differences between groups in body mass index, waist circumference and triglycerides. Other
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br Results br Discussion Fetal
2020-05-08
Results Discussion Fetal development occurs under conditions of low oxygen tension and steady maternal glucose such that physiologic systems including the pancreas are functionally poised in the prenatal state. Postnatally, oxidative metabolism becomes dominant and intermittent feeding exposes
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Structure similarity searches were conducted using the stand
2020-05-07
Structure similarity searches were conducted using the standalone version of the DALI program with the query structures scanned against a local current version of the PDB that has all chains as separate entries (Holm and Sander, 1995). The structural hits for each query were collected, even if the D
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Regarding the effects of CRF on
2020-05-07
Regarding the effects of CRF on anxiety, Sahuque et al. (2006) have demonstrated that this neuropeptide also enhances anxiety when injected into the bed nucleus of the stria terminalis (BNST), a NECA structure that has also been related to defensive behavior (Casada and Dafny, 1991, Chen et al., 20
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While lowering the TID exposure of electronics
2020-05-07
While lowering the TID exposure of electronics is fairly straightforward, there are other 6-Bnz-cAMP sodium salt mg induced effects that are not as easily mitigated, especially with COTS components. Single Event Effects (SEE) occur when a high-energy particle strikes the active area of an integrate
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While oxysterols were most extensively studied for its
2020-05-06
While oxysterols were most extensively studied for its potent ability to mediate feedback regulation of cholesterol biosynthesis, some early investigations showed that the enzymes involved in its syntheses were highly upregulated in macrophages and dendritic cells—an indication of possible roles in
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br Materials and methods br Results br
2020-05-06
Materials and methods Results Discussion Regardless of obvious beneficial effects of GC on acceleration of foetal lung and cardiomyocytes maturation (Kamath-Rayne et al., 2012; Rog-Zielinska et al., 2015), the current study revealed that GC exposure during late pregnancy induces IR and alte
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Does a universal mechanism for TLS exist Our previous studie
2020-05-06
Does a universal mechanism for TLS exist? Our previous studies using the bacteriophage T4 DNA polymerase generated the model provided in Fig. 7 that quantifies the molecular forces influencing key steps in the polymerization pathway during the replication of a non-instructional versus miscoding DNA
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Like compound substitution on compound contains amino
2020-05-06
Like compound substitution on compound () contains amino and carboxamide groups attached to adjacent ring positions. These groups have similar interactions as compound with the protein backbone and Glu114. The triazole core is coordinated with Lys291. The triazole ring core π-stacks with Tyr226.
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Although the formation and toxicity of DPC is theoretically
2020-05-06
Although the formation and toxicity of DPC is theoretically acceptable, it is difficult to evaluate the specific role of DPC and its repair enzyme MGMT in the cytotoxic and mutagenic effects because DPCs are estimated to constitute only 1%–3% of total DNA damage when varlitinib are exposed to bis-e
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Acknowledgments br Prostaglandin D PGD plays a key role
2020-05-06
Acknowledgments Prostaglandin D (PGD) plays a key role in mediating allergic reactions such as those seen in asthma, allergic rhinitis, atopic dermatitis and allergic conjunctivitis. PGD is the major cyclooxygenase product formed and secreted by activated mast cells and its levels in bronchoalveo
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